QLTI-26. INTEGRATION OF NEURO-ONCOLOGY CLINICAL PATHWAYS IN PROVIDENCE SOUTHERN CALIFORNIA CLINICAL RESEARCH NETWORK

Novel clinical trials in neuro-oncology

Clinical research within neuro-oncology is complicated by several factors, including complex tumor biology and a variable impact on patients, as a consequence both of disease location and degree of malignancy. Clinical studies are complicated by these factors as well as issues of determining optimal clinical end points. This review highlights relevant aspects of neurooncologic diseases, includi...

Clinical and Outcome Research in oncology The need for integration

Cancer is one of the main healthcare problems in Europe. Although significant progress has recently been made, long-term survival is still disappointing for most common solid tumours. The explosion of information has strengthened the need to create and sustain coordinated interaction between technology, biology, clinical research, clinical practice and health policy. A simple process based on a...

Clinical Relevance of Steroid Use in Neuro-Oncology.

BACKGROUND Corticosteroids are commonly used in the management of primary central nervous system (CNS) tumors and CNS metastases to treat cancer- and treatment-related cerebral edema and improve neurologic function. However, they are also associated with significant morbidity and mortality, given their wide range of adverse effects. PURPOSE OF REVIEW To review the mechanism of action, pharmac...

American Society of Clinical Oncology Criteria for High-Quality Clinical Pathways in Oncology.

Model-based Integration of Clinical Practice Guidelines in Clinical Pathways

Healthcare providers are facing an enormous cost pressure and a scarcity of resources, so that they need to realign in the tension between economic efficiency and demand-oriented healthcare. Clinical Practice Guidelines (CPGs) and clinical pathways have been established to improve the quality of care and to reduce costs at the same time. CPGs have a positive impact on the health outcome. Howeve...